The paper detailing the architectural decisions behind the Open PHACTS Discovery Platform has been published (Gray et al., 2014).
Applying linked data approaches to pharmacology: Architectural decisions
and implementation
Gray, Alasdair J. G. and Groth, Paul T. and Loizou, Antonis and Askjaer, Sune and Brenninkmeijer, Christian Y. A. and Burger, Kees and Chichester, Christine and Evelo, Chris T. A. and Goble, Carole A. and Harland, Lee and Pettifer, Steve and Thompson, Mark and Waagmeester, Andra and Williams, Antony J.
Semantic Web Journal, 5(2):101–113, 2014
The discovery of new medicines requires pharmacologists to interact with a number of information sources ranging from tabular data to scientific papers, and other specialized formats. In this application report, we describe a linked data platform for integrating multiple pharmacology datasets that form the basis for several drug discovery applications. The functionality offered by the platform has been drawn from a collection of prioritised drug discovery business questions created as part of the Open PHACTS project, a collaboration of research institutions and major pharmaceutical companies. We describe the architecture of the platform focusing on seven design decisions that drove its development with the aim of informing others developing similar software in this or other domains. The utility of the platform is demonstrated by the variety of drug discovery applications being built to access the integrated data.
@article{Gray:OPS:SWJ,
author = {Gray, Alasdair J. G. and Groth, Paul T. and Loizou, Antonis and Askjaer, Sune and Brenninkmeijer, Christian Y. A. and Burger, Kees and Chichester, Christine and Evelo, Chris T. A. and Goble, Carole A. and Harland, Lee and Pettifer, Steve and Thompson, Mark and Waagmeester, Andra and Williams, Antony J.},
title = {Applying linked data approaches to pharmacology: Architectural decisions
and implementation},
journal = {Semantic Web Journal},
volume = {5},
number = {2},
pages = {101--113},
year = {2014},
url = {https://doi.org/10.3233/SW-2012-0088},
doi = {10.3233/SW-2012-0088}
}
About Me
I'm an Associate Professor in Computer Science at Heriot-Watt University. My research focuses on linking datasets.
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